Based on Jeff Lindsay's novels Darkly Dreaming Dexter and Dearly Devoted Dexter this crime thriller follows Dexter Morgan. Dexter is a forensic blood spatter expert for the Miami Dade Police Department. He is the main support for his sister. He has a steady girlfriend, with two kids who adore him. He also has an active "night life". Based on a code instilled in him by his foster father, Harry, he hunts down people who have escaped justice and makes sure they don't get away with a crime again.
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By aiding Lumen, Dexter puts himself on a collision course with Debra and the homicide division, and things get worse when he's brought in to work a horrific crime scene; Debra's investigation into the Santa Muerte killings leads her into a deadly confrontation with the killers.