"Charlie is a well-to-do bachelor with a house at the beach, a Jaguar in the front, and an easy way with women. His casual Malibu lifestyle is interrupted when his tightly wound brother Alan, who's facing a divorce, and his son Jake, come to live with him. Together, these two and a half men confront the challenges of growing up; finally. Complicating matters are the brothers' self-obsessed, controlling mother, Evelyn, Alan's estranged wife, Judith and Charlie's crazy neighbor Rose, who wants to be a part of his life and is willing to do anything to be around. Known in Germany as Mein cooler Onkel Charlie (My Cool Uncle Charlie)."
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When a drunken Charlie ruins his time with a girl, Jake retaliates by convincing Alan to invite Evelyn to the house for her birthday dinner, to which Russell is subsequently invited when he and Evelyn seem to hit it off at the pharmacy.